Metabolomics Core Publications

Selected Publications Supported by the Metabolomics Core

2025

  1. Sahu U, Mullarkey MP, Murphy SA, Anderson JC, Putluri V, Kamal AHM, Park JH, Lee TJ, Ling AL, Kaipparettu BA, Sharma A, Putluri N, Wenzel PL, Willey CD, Chiocca EA, Markert JM, Kaur B. IDH status dictates oHSV mediated metabolic reprogramming affecting anti-tumor immunity. Nat Commun. 2025 Apr 24;16(1):3874. doi: 10.1038/s41467-025-58911-2. PMID: 40274791; PMCID: PMC12022073.
  2.  Wooton-Kee CR, Yalamanchili HK, Mohamed I, Hassan M, Setchell KDR, Narvaez Rivas M, Coskun AK, Putluri V, Putluri N, Jalal P, Schilsky ML, Moore DD. Changes in the FXR-cistrome and alterations in bile acid physiology in Wilson disease. Hepatol Commun. 2025 May 23;9(6):e0707. doi: 10.1097/HC9.0000000000000707. PMID: 40408300; PMCID: PMC12106221.
  3. Yadollahi P, McCord KA, Li Y, Dayoub H, Saab K, Essien F, Hyslop S, Kan E, Ahmed KM, Kirby PR, Putluri V, Ambati CSR, Kami Reddy KR, Castro P, Skinner HD, Coarfa C, Decker WK, Osman AA, Patel R, Myers JN, Lai SY, Putluri N, Johnson FM, Frederick MJ, Hudson WH, Sandulache VC. Bypassing cisplatin resistance in Nrf2 hyperactivated head and neck cancer through effective PI3Kinase targeting. Br J Cancer. 2025 Dec;133(12):1802-1814. doi: 10.1038/s41416-025-03189-w. Epub 2025 Oct 6. PMID: 41053162; PMCID: PMC12690143.
  4. Yao TH, Treekitkarnmongkol W, Putluri N, Sankaran D, Nguyen T, Balasenthil S, Hurd MW, Chen M, Brand RE, Lampe PD, Kamal AHM, Putluri V, Hu TY, Maitra A, Koay EJ, Killary AM, Sen S, Kundu S. Machine learning-based multimodal biomarkers enable accurate diagnosis and early detection of pancreatic ductal adenocarcinoma. Sci Rep. 2026 Jan 7;16(1):658. doi: 10.1038/s41598-025-29548-4. PMID: 41495079; PMCID: PMC12780069.
  5. Park JH, Jung KH, Jia D, Yang S, Attri KS, Ahn S, Murthy D, Samanta T, Dutta D, Ghidey M, Chatterjee S, Han SY, Pedroza DA, Tiwari A, Lee JV, Davis C, Li S, Putluri V, Creighton CJ, Putluri N, Dobrolecki LE, Lewis MT, Rosen JM, Onuchic JN, Goga A, Kaipparettu BA. Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway. Cell Rep Med. 2025 Feb 18;6(2):101941. doi: 10.1016/j.xcrm.2025.101941. Epub 2025 Feb 10. PMID: 39933530; PMCID: PMC11866546.
  6. Cao C, Gong W, Shuai Y, Rasouli S, Ge Q, Khan A, Dakic A, Putluri N, Shvets G, Zheng YL, Daneshdoust D, Mahyoob R, Li J, Liu X. Canonical and non-canonical functions of the non-coding RNA component (TERC) of telomerase complex. Cell Biosci. 2025 Mar 1;15(1):30. doi: 10.1186/s13578-025-01367-0. PMID: 40025596; PMCID: PMC11871756.
  7. Chan YS, Gao Q, Robinson SA, Wang W, Filandrova R, Weinhold LM, Cabrera ML, Zhang M, Ambati CSR, Lerario AM, Putluri N, Kiseljak-Vassiliades K, Wierman ME, Habra MA, Hammer GD, Veverka V, Cermakova K, Hodges HC. β-catenin functions as a molecular adapter for disordered cBAF interactions. Mol Cell. 2025 Aug 21;85(16):3041-3056.e9. doi: 10.1016/j.molcel.2025.06.026. Epub 2025 Jul 21. PMID: 40695292; PMCID: PMC12323811.
  8. Elbialy A, Sood A, Wang SJ, Wang P, Fadiel A, Parwani AV, Huang S, Shvets G, Putluri N, Li J, Liu X. Unveiling racial disparities in prostate cancer using an integrative genomic and transcriptomic analysis. Cell Insight. 2025 Feb 17;4(2):100238. doi: 10.1016/j.cellin.2025.100238. PMID: 40104216; PMCID: PMC11914995.
  9. Hudobenko J, Di Gesù CM, Mooz PR, Petrosino J, Putluri N, Ganesh BP, Rebeles K, Blixt FW, Venna VR, McCullough LD. Maternal dysbiosis produces long-lasting behavioral changes in offspring. Mol Psychiatry. 2025 May;30(5):1847-1858. doi: 10.1038/s41380-024-02794-0. Epub 2024 Oct 23. PMID: 39443733; PMCID: PMC12014497.
  10. Hummel G, Banerjee S, Putluri V, Malick I, Johnson G, Kamal AHM, Ambati CSR, Putluri N, Showalter L, Shope CD, Hagan J, Aagaard KM, Moorthy B, Suter MA. Placental Polycyclic Aromatic Hydrocarbon (PAH) Levels Are Associated with Spontaneous Preterm Birth. Int J Mol Sci. 2025 Aug 23;26(17):8179. doi: 10.3390/ijms26178179. PMID: 40943106; PMCID: PMC12428254.
  11. Lee S, Jung SY, Kuś P, Bondaruk J, Lee JG, Jaksik R, Putluri N, Dinh KN, Cogdell D, Chen H, Wang Y, Chen J, Navai N, Dinney C, Mendelsohn C, McConkey D, Behringer RR, Guo CC, Wei P, Kimmel M, Czerniak B. Dysregulated mitochondrial energy metabolism drives the progression of mucosal field effects to invasive bladder cancer. J Pathol. 2025 Nov;267(3):329-346. doi: 10.1002/path.6474. Epub 2025 Sep 25. PMID: 40996337; PMCID: PMC12531120.
  12. Razavi S, Khan A, Fu DX, Mayer D, McConkey D, Putluri N, Siddiqui MM. Metabolic landscape in bladder cancer. Curr Opin Oncol. 2025 May 1;37(3):259-266. doi: 10.1097/CCO.0000000000001137. Epub 2025 Mar 11. PMID: 40071441.
  13. Wang H, Liang Y, Boor PJ, Khanipov K, Zhang Y, Yu X, Ambati CSR, Putluri N, Khan MF. Protective Role of Dietary Short-Chain Fatty Acid Propionate against Autoimmune Responses and Pathology of Systemic Lupus Erythematosus in MRL-lpr Mice. J Nutr. 2025 Jul 2;155(9):3116–27. doi: 10.1016/j.tjnut.2025.06.031. Epub ahead of print. PMID: 40615087; PMCID: PMC12797317.